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	Bioinformatics by D.R. Westhead, J.H. Parish & R.M. Twyman
	Price : Rs 375.00
	Your Price : Rs 337.50

Instant notes in Bioinformatics is a concise yet comprehensive book for undergraduates, postgraduates and researchers who need to learn about this dynamic field. All the important areas in bioinformatics are covered in a format that is ideal for learning and rapid revision.

Contents: Section A – Overview of bioinformatics • The scope of bioinformatics • Bioinformatics and the internet • Useful bioinformatics sites on the www • Section B – Data acquisition • Sequencing DNA, RNA and proteins • Determination of protein structure • Gene and protein expression data • Protein interaction data • Section C – Databases – contents, structure and annotation • File formats • Annotated sequence databases • Genome and organism-specific databases • Miscellaneous databases • Section D – Retrieval of biological data • Data retrieval with Entrez and DBGET/LinkDB • Data retrieval with SRS (sequence retrieval system) • Section E – Searching sequence databases by sequence similarity criteria • Sequence similarity searches • Amino acid substitution matrices • Database searches: FASTA and BLASTA Sequence filters • iterative database searches and PSI-BLAST • Section F – Multiple sequence alignment: gene and protein families • Multiple sequence alignment and family relationships • Protein families and pattern databases • Protein domain families • Section G – Phylogenetics • Phylogenetics, cladistics and ontology • Building phylogenetic trees • Evolution of macromolecular sequences • Section H – Sequence annotation • Principles of genome annotation • Annotation tools and resources • Section I – Structural bioinformatics • Conceptual models of protein structure • The relationship of protein three-dimensional structure to protein function • The evolution of protein structure and function • Obtaining, viewing and analyzing structural data structural alignment • Classification of proteins of known three-dimensional structure: CATH and SCOP • Introduction to protein structure prediction • Structure prediction by comparative modeling • Secondary structure prediction and prediction strategies • Section J – Microarray data analysis • Microarray data: analysis methods • Microarray data: tools and resources • Sequence sampling and SAGE • Section K – Proteomic data analysis • Analyzing data from 2D-PAGE gels • Analyzing protein mass spectrometry data • Section L – Higher-order systems • Modeling and reconstructing molecular pathways • Protein interaction informatics • Higher-order models • Section M - Cheminformatics in biology • Conventions for representing molecules • Cheminformatics resources • Section N - Bioinformatics in the pharmaceutical industry • Bioinformatics and drug discovery • Pharmainformatics resources • Section O • Basic principles of computing in bioinformatics • Running computer software • Computer operating systems • Software downloading and installing • Database management.

ISBN - 9781859962725

Pages : 272

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Bioinformatics

by D.R. Westhead, J.H. Parish & R.M. Twyman