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Cytochrome P450 And Other Enzymes In Drug Discovery And Development
by Jae Lee, R. Scott Obach
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Critical in the elimination of drugs and other xenobiotics from the body, cytochrome P450 has strong bearing on scientific assessments of genetic polymorphism in metabolism, possible drug-drug interactions, and bioavailability of candidate drugs. This text systematizes findings on P450 and similar enzymes - as well as parallel issues shaping the pharmaceutical industry - to promote the next generation of safer, more effective drugs.ISBN-9780824742935
Pages : 608
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